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ClearRounds Health · Cardiology · Quick Reference

WPW / Pre-excitation

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Arrhythmias & DevicesIntermediateIn progressOne-page PDF

ECG recognition, risk features, AF with WPW warning, medication cautions, and EP referral.

Last reviewed

Pending initial clinical review

Sources / guidelines to verify

  • 2015 ACC/AHA/HRS SVT Guideline (pre-excitation section)
Disclaimer: Educational reference only. Not a substitute for clinician judgment, local protocols, or current guideline review.

One-page reference

Draft content pending the site owner’s clinical review. Verify against the sources above and local protocol before clinical use.

1

What it is / why it matters

  • An accessory pathway causes pre-excitation and a risk of SVT (AVRT).
  • The danger: rapid conduction of atrial fibrillation down the pathway → VF.
2

Key diagnostic clues

  • ECG in sinus: short PR + delta wave + wide QRS.
  • AVRT = regular SVT; AF with WPW = wide, irregular, and very fast.
3

Initial workup

  • 12-lead ECG, echo; EP study for risk stratification in high-risk features, athletes, or certain occupations.
4

Management framework

  • Stable AVRT: vagal maneuvers/adenosine.
  • Definitive treatment is catheter ablation of the pathway (high success).
5

Red flags / escalate now

  • AF with pre-excitation → AVOID AV-nodal blockers (adenosine, beta-blockers, CCBs, digoxin) → procainamide or cardioversion.
  • Syncope or a very short pre-excited RR interval → urgent EP.
6

Follow-up / monitoring

  • EP referral; post-ablation follow-up.
7

Clinic pearls

  • AF + WPW is the danger scenario — no AV-nodal blockers.
  • Ablation is curative; refer symptomatic and high-risk asymptomatic patients.

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ClearRounds Health · Cardiology — WPW / Pre-excitation Quick Reference · Last reviewed: Pending initial clinical review · Educational reference only. Not a substitute for clinician judgment, local protocols, or current guideline review.