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ClearRounds Health · Cardiology · Quick Reference

Cardiac Sarcoidosis

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Heart Failure & CardiomyopathyAdvancedIn progressOne-page PDF

Suspicion triggers, conduction disease/VT/HF clues, MRI/PET role, immunosuppression referral, ICD considerations.

Last reviewed

Pending initial clinical review

Sources / guidelines to verify

  • HRS Expert Consensus on Cardiac Sarcoidosis
  • AHA/ACC arrhythmia & device guidelines (ICD indications)
Disclaimer: Educational reference only. Not a substitute for clinician judgment, local protocols, or current guideline review.

One-page reference

Draft content pending the site owner’s clinical review. Verify against the sources above and local protocol before clinical use.

1

What it is / why it matters

  • Granulomatous infiltration of myocardium → conduction disease, VT, and heart failure.
  • Often accompanies systemic sarcoidosis but can be isolated.
2

Key diagnostic clues

  • Unexplained AV block in a patient <60.
  • Ventricular tachycardia or new cardiomyopathy.
  • Known pulmonary sarcoid with cardiac symptoms; patchy LV dysfunction.
3

Initial workup

  • ECG/telemetry, echo, cardiac MRI (late gadolinium enhancement) and/or FDG-PET (active inflammation).
  • Evaluate extracardiac sarcoid (chest imaging; biopsy an accessible node when possible).
4

Management framework

  • Immunosuppression (corticosteroids ± steroid-sparing agents) for active inflammation, via specialist.
  • HF GDMT; low threshold for ICD (VT, high-grade block, or low EF).
  • EP referral for ventricular arrhythmia.
5

Red flags / escalate now

  • High-grade AV block, VT/VF, or syncope → urgent monitoring + EP/ICD evaluation.
6

Follow-up / monitoring

  • PET to track inflammation/treatment response; device checks; multidisciplinary care.
7

Clinic pearls

  • Unexplained AV block in a young patient → think sarcoid (and Lyme).
  • The ICD threshold is low; MRI and PET are complementary.

Related quick references

📄 Cardiomyopathy Overview: Dilated, Hypertrophic, Restrictive📄 AV Block📄 Ventricular Tachycardia / Ventricular Fibrillation📄 ICDs

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ClearRounds Health · Cardiology — Cardiac Sarcoidosis Quick Reference · Last reviewed: Pending initial clinical review · Educational reference only. Not a substitute for clinician judgment, local protocols, or current guideline review.